Medicine Recommendations

Ocular symptoms of cystinosis

Ulcerative colitis and Crohn's ONLY; only for inflammatory bowel diseases when patients are unable to tolerate azathioprine.

Ulcerative colitis

Reduction in the risk or delay of the onset of type 2 diabetes mellitus in adult, overweight patients with implied Glucose Tolerance and/or increased HbA1C who are at high risk for developing overt type 2 diabetes mellitus and still progressing towards type 2 diabetes mellitus despite implementation of intensive lifestyle change for 3-6 months

Treatment of type 2 diabetes mellitus, particularly in overweight patients, when dietary management and exercise alone does not result in adequate glycaemic control

Rheumatic diseases

Crohn's Disease

Rheumatoid Arthritis

Severe Active Juvenile Idiopathic Arthritis

Severe Eczema, Lichen Planus, Felty’s syndrome (unlicensed)

Severe Psoriasis

Severe Psoriatic Arthritis

Opioid induced bowel dysfunction in palliative care (NICE TA 277 terminated)

NICE is unable to recommend the use in the NHS because no evidence submission was received from the manufacturer of the technology

NICE TA277 - Methylnaltrexone for treating opioid-induced bowel dysfunction in people with advanced illness receiving palliative care (terminated appraisal)

ADHD in children, adolescents and adults

NICE guideline NG87: Attention deficit hyperactivity disorder: diagnosis and management

Acute Gout (as per LSCMMG Guidelines)

Nausea associated with Acute Migraine

MHRA Drug Safety Update - Metoclopramide: risk of neurological adverse effects

Nausea and vomiting

Opioid-induced nausea and vomiting

Treatment of patients with chronic heart failure with resistant volume overload.

Treatment of documented ventricular arrhythmias which, in the judgement of the physician, are considered as life-threatening.

Depressive illness

The colour classification was determined as part of the collaborative work between LCFT and medicines Management leads. Local pathways and patient safety were taken into consideration.