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Dapagliflozin

Amber level 0

Brand:

Nice TA:

679

Commissioning responsibility:

CCG

PbR excluded:

No

BNF chapter:
Cardiovascular system

Background

1.1 Dapagliflozin is recommended as an option for treating symptomatic chronic heart failure with reduced ejection fraction in adults, only if it is used as an add-on to optimised standard care with:

  • angiotensin-converting enzyme (ACE) inhibitors or angiotensin‑2 receptor blockers (ARBs), with beta blockers, and, if tolerated, mineralocorticoid receptor antagonists (MRAs), or
  • sacubitril valsartan, with beta blockers, and, if tolerated, MRAs.

Recommendation

LSCMMG Recommendation:

Amber level 0

Reason for decision:

Suitable for GP prescribing following recommendation/initiation by specialist

Supporting documents:

Decisions of Lancashire local decision making groups

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Last Updated: 11 - Mar - 2021