Sotagliflozin with insulin
Amber level 0
Brand:
Nice TA:
622
Commissioning responsibility:
CCG
PbR excluded:
No
BNF chapter:
Endocrine system
Background
1.1 Sotagliflozin with insulin is recommended as an option for treating type 1 diabetes in adults with a body mass index (BMI) of at least 27 kg/m2 , when insulin alone does not provide adequate glycaemic control despite optimal insulin therapy, only if:
- sotagliflozin is given as one 200 mg tablet daily
- they are on insulin doses of 0.5 units/kg of body weight/day or more and
- they have completed a structured education programme that is evidence based, quality assured, delivered by trained educators and includes information about diabetic ketoacidosis, such as:
- how to recognise its risk factors, signs and symptoms
- how and when to monitor blood ketone levels
- what actions to take for elevated blood ketones and
- treatment is started and supervised by a consultant physician specialising in endocrinology and diabetes treatment, and haemoglobin A1c (HbA1c) levels are assessed after 6 months and regularly after this.
Recommendation
LSCMMG Recommendation:
Amber level 0
Reason for decision:
Suitable for GP prescribing following recommendation/initiation by specialist
Supporting documents: