Tolvaptan
Indication
Treatment of hyponatremia in adults, secondary to the syndrome of inappropriate antidiuretic hormone secretion (SIADH), for patients not requiring chemotherapy.
Red
Brand:
Samsca
Nice TA:
Commissioning responsibility:
CCG
PbR excluded:
Yes
BNF chapter:
Endocrine system
Background
Recommendation: RED for the following indications:
Treatment of hyponatremia in adults, secondary to the syndrome of inappropriate antidiuretic hormone secretion (SIADH), only if:
- Treatment is initiated, titrated and monitored in hospital, by a specialist experienced in the treatment of SIADH, and
- Fluid restriction has been unsuccessful or is inappropriate, and
- Treatment with demeclocycline has been unsuccessful or is inappropriate.
Recommendation
LSCMMG Recommendation:
Red
Reason for decision:
Specialist medicine
Supporting documents: